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Summary of reporting by Ars Technica • • 1 min read
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Study finds millions of Americans using GLP-1 medications in unapproved ways

A CDC study indicates that around 27 million US adults used GLP-1 medications in 2025, with many altering their usage due to cost and availability issues. Nearly half of the users reported using the drugs differently than prescribed.

A recent study from the CDC shows that approximately 27 million adults in the US used GLP-1 medications in 2025, with many not following prescribed guidelines. The study found that 44 percent of users modified their usage, often due to cost and availability challenges. Younger adults aged 14–39 were particularly affected, with a significant percentage citing cost as a barrier to proper use.

Key facts

  • 9.8 percent of US adults used GLP-1 medications in 2025.
  • Approximately 27 million adults are estimated to have used GLP-1 drugs.
  • 44 percent of GLP-1 users altered their usage from prescriptions.
  • 58 percent of younger users cited cost as a barrier to proper use.
  • The study was published in the CDC's Morbidity and Mortality Weekly Report.
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Original vs. Neutral

Original Headline

Millions in US use unapproved GLP-1s—and use them in unapproved ways

Neutral Headline

Study finds millions of Americans using GLP-1 medications in unapproved ways