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FDA Approves Third Over-the-Counter Naloxone Nasal Spray

The FDA has approved Rextovy, a 4 milligram naloxone nasal spray, making it the third over-the-counter version available for the emergency treatment of opioid overdose. This product will be accessible for purchase in various retail locations.

The Food and Drug Administration (FDA) approved a third over-the-counter version of naloxone nasal spray on June 16, 2026. The newly approved product, Rextovy, contains 4 milligrams of naloxone and is intended for the emergency treatment of opioid overdose. Consumers will be able to purchase it directly from pharmacies, convenience stores, and online.

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FDA approves third over-the-counter opioid overdose nasal spray

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FDA Approves Third Over-the-Counter Naloxone Nasal Spray